Detalhe da pesquisa
1.
XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6.
Hum Mol Genet
; 31(15): 2639-2654, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35333353
2.
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2.
J Biol Chem
; 298(8): 102228, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787375
3.
A transgenic mouse line for assaying tissue-specific changes in endoplasmic reticulum proteostasis.
Transgenic Res
; 32(3): 209-221, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37133648
4.
The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy.
J Biol Chem
; 297(4): 101191, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520759
5.
SAXS study of the formation and structure of polynuclear thorium(IV) colloids and thorium dioxide nanoparticles.
J Synchrotron Radiat
; 29(Pt 2): 281-287, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254289
6.
Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor.
J Chem Inf Model
; 62(5): 1249-1258, 2022 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35103473
7.
Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome.
Proc Natl Acad Sci U S A
; 116(28): 14154-14163, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31235574
8.
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays.
J Biol Chem
; 295(12): 4001-4013, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034092
9.
KDM5 histone demethylases repress immune response via suppression of STING.
PLoS Biol
; 16(8): e2006134, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30080846
10.
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
J Biol Chem
; 294(46): 17654-17668, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481464
11.
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2.
J Biol Chem
; 293(35): 13750-13765, 2018 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945974
12.
Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation.
J Am Chem Soc
; 141(21): 8450-8461, 2019 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31059257
13.
Neurons Internalize Functionalized Micron-Sized Silicon Dioxide Microspheres.
Cell Mol Neurobiol
; 37(8): 1487-1499, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28260198
14.
Optogenetic inhibition of dorsal medial prefrontal cortex attenuates stress-induced reinstatement of palatable food seeking in female rats.
J Neurosci
; 33(1): 214-26, 2013 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23283335
15.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors.
J Biol Chem
; 288(6): 4209-25, 2013 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23255601
16.
Human serum albumin binding to silica nanoparticles--effect of protein fatty acid ligand.
Phys Chem Chem Phys
; 16(21): 10157-68, 2014 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24595605
17.
Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded ß-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease.
bioRxiv
; 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712038
18.
Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis.
bioRxiv
; 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38529509
19.
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice.
Cell Rep
; 43(5): 114144, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656874
20.
Toward absolute abundance for conservation applications: Estimating the number of contributors via microhaplotype genotyping of mixed-DNA samples.
Mol Ecol Resour
; 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37254815